@ugadawg1067, Welcome to Connect. I requested that your post about liver related itching to be added to this discussion where other members have shared their concerns and also and also some solutions that they discovered to be helpful to them.
I am a transplant recipient and I also had severe itching as my liver disease progressed toward transplant.
My transplant, in 2009, was due to Primary Sclerosing Cholangitis (PSC) and hepatorenal failure. I remember that my itching began near the time that I was referred to the transplant department by my local GI who had managed my care for nearly 8 years. And I remember the terrible itch! The door frames in our house became my scratching posts - much like a bear uses a tree. I fortunately never broke any skin as I had read that some patients do.
I am so very sorry that you are having itching. I assure you that you are not alone.
Here is a list of some things - remedies - that I tried:
- Over-the-counter antihistamine
- When my itching became severe, my local GI wrote a prescription for Chlorestyramine, a bilebinder and that gave me the relief I needed. It was a powder that I added to a glass of water and drank.
- topical relief – I got some relief with Sarna anti itch lotion. It is an over the counter lotion.
- a warm bath in Aveeno bath treatment for itchy skin was helpful and soothing, but getting in and out of the tub, quickly became difficult as my body became swollen with ascites.

I don't remember when or why, but sometime during my pretransplant time, my itching eased as other bothersome symptoms took over.

Here is another discussion that has more itchy solutions:
Kidney & BladderItchy skin
https://connect.mayoclinic.org/discussion/itchy-skin-2ee1a9/

I want to suggest that you read thru this discussion and the one that I have posted. I also want to let you know that your questions and comments are welcomed anywhere. If you want to direct a question to any particular member, use their @name.

I don't know if there are any newer remedies available. I look forward to hearing from some members with any updates for itchy solutions.

@ugadawg1067 How long has your itching been going on? Have you tried a warm bath before bed?

@ugadawg1067 around the time I got listed my itching was about as bad as yours. When the cream and the cholestyramine drink powder stopped working one of the transplant hepatologists prescribed Zoloft for me to try. While the Zoloft did absolutely stop the itching, it came with some side effects that were not desirable. They backed me off of what they had originally prescribed which still worked with less intense side effects. You may want to ask about that, just make sure to ease into it with their guidance. Good luck, I know like many of us do what that intense itching was like. When it started ruining my sleep that was really the last straw. Keep us posted and we’ll all pray that you’ll get your transplant soon. That, seems to be the only cure for the itching.

Be well,

Bryan