Hi @nottoday. It sounds like you have a lot going on and are searching for answers in several different places. You'll notice that I merged your 3 posts into one discussion that appears in the Autoimmune Diseases group as well as the Bones, Joints & Muscles group. I did this so you can easily connect with others who may have had similar issues and so you can gather insights from others in one place.

I'd like to bring @oumike into the discussion as he has experience with Paget's disease. @pattymac @megansims may be able to offer some insights about mediastinal lymphadenopathy. And @johnbishop is familiar with inflammatory issues and autoimmune conditions.

@nottoday, what specialists did the testing? Are the investigations being led by oncology at the moment?