That's the rub...when I started last June I was told "this is the only bone density med you'll ever have to take again." Since Evenity was new, I guess that was the thinking. Now I've been told that in a year I will have to have an infusion of ?; I hear infusion and I think chemo. That may be incorrect, but I hear that there's some chemo in several bone medicines, and I just don't want that. ..so much for listening to doctors. We seem to have agreed that weekly Actonal is what I'll be taking, since I had it for years before without any issues.