I took Anastrazole for 5 years with no major issues but the biggest thing you need to remember is that everyone is different and how medication effects you, may be be different from someone else. My side effects happened over time and didn’t last long from the time they started. I had hair thinning but it wasn’t noticeable. My hair stylist would tell me and recommend using certain hair products but again I didn’t notice that much and if you’re stressed, that can also cause side effects like fatigue but I would always remind myself of why I am on this drug and how it will benefit me in the long run. Take care!