Just for balance, I will again say that I took letrozole for 5 years with little joint pain and found it very tolerable. I miss it, because it made me feel secure!

I am sorry for those who suffered on these meds but for others reading this forum, many of my friends also did 5 years relatively comfortably.

We all have different risks and have had different cancers and treatments. And some of us do want quantity of life versus quality to be around for our kids! So motivation varies.

I tried generic anastrazole first and reacted immediately to the ingredients. This is a sensitivity and different from a side effect over time. I switched to letrozole and then to brand name and was fine. Exercising 45 minutes minimum helped what few pains I had, but exercising for less than that tended not to help.