Hi @dsd1939, Oh golly, you and your wife are sure having to endure an epic cancer journey. She’s so very fortunate to have such a supportive and loving husband. I know it’s not easy being the caregiver. It can be emotionally and physically draining so I hope you also have some support.

Your wife as had a feeding tube for quite some time. Is this the first she’s experiencing shivering and shaking? Has the temperature of her formula changed? Does the solution feel quite cold? Hyperthermia would seem unlikely because the food would need to be very cold to cause that. Though if it is colder than usual it could be much like drinking cold milk or a milk shake that can chill the body. But that would generally be short lived.

I’m wondering more if it’s the reaction of the radiation and chemo giving her the chills. Our bodies can react to these medications and treatments with shivering. I had certain chemo therapy infusions where I needed several of the wonderful heated hospital blankets piled on me for several hours to feel warm because I’d be shaking intensely.
Is your wife home? If so, you could toss some blankets in the clothes dryer to heat them up and wrap her. A heating pad or hot water bottles are a good way to warm her too. Just make sure there is a towel between her skin and the pad for protection.

Also, could your wife possibly have an elevated temperature? You could check for a fever just to make sure.
Have you spoken to her oncologist about her reaction?