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Neuropathy | Last Active: Nov 3 12:52pm | Replies (538)

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@mrsmary

I recently had my 2nd Shingrix shot, it did not worsen my neuropathy which for me started shortly after I begsn taking Anastrozole. I switched to Letrozole and my other side effects trigger finger, De Quervain’s Tenosynovitis resolved after another 6 weeks of PT, but the neuropathy has never improved.

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Replies to "I recently had my 2nd Shingrix shot, it did not worsen my neuropathy which for me..."

John, Volunteer Mentor | @johnbishop | May 13, 2022

Welcome @mrsmary, You mentioned your neuropathy started shortly after taking Anastrozole and then you switched to Letrozole. I did see an article that may explain the connection to neuropathy --- "Do aromatase inhibitors cause neuropathy?
Another mechanism is that AI could have caused SjS and neuropathy or triggered the onset of subclinical SjS in this patient. SjS may have mostly subclinical course, and the diagnosis of SjS is delayed because of this subclinical course." --- Does Aromatase Inhibitors Cause Sjogren’s Syndrome and Polyneuropathy?: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649745/

Has your doctor offered any treatments to help with the neuropathy symptoms?

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