I'm not taking any of these but have been researching them in case I need to if my current osteopenia takes a darker turn (as I consider osteoporosis). Ivevalso consulted with two endocrinologist about the current array of drugs for osteoporosis and some promising alternatives to DEXA scans in the future as they are less than optimally accurate.

Did your doctor discuss the array of choices for meds and explain the benefits (and side effects) of the categories or just give you the two options?

I am curious why you are deciding between Prolia and Evenity, which are made by the same company. I would ask about Forteo or Tymlos, which grow bone without suppressing turnover.

Here is the black box warning for Evenity. If you have not had a stroke or heart attack and are not at high risk for either, you could consider Evenity too.

POTENTIAL RISK OF MYOCARDIAL INFARCTION, STROKE, AND CARDIOVASCULAR DEATH
EVENITY® may increase the risk of myocardial infarction, stroke and cardiovascular death. EVENITY® should not be initiated in patients who have had a myocardial infarction or stroke within the preceding year. Consider whether the benefits outweigh the risks in patients with other cardiovascular risk factors. Monitor for signs and symptoms of myocardial infarction and stroke and instruct patients to seek prompt medical attention if symptoms occur. If a patient experiences a myocardial infarction or stroke during therapy, EVENITY® should be discontinued.