Ibrance and Letrozole: Newly Diagnosed Treatment

I have been on verzenio (2 x day) and anastrozole 1mg a day for over a year. Went recently for second opinion. Oncologist took me off the verzenio and anastrozole. She did this because I told her about diarrhea and vomiting and no energy. I wondering what kind of results other patients have had with Ibrance and Letrozole. I have read life expectancy not as good with Ibrance compared to Verzenio. The Ibrance I am to take 28 days then go off 7 days and restart cycle of 28 days on, 7 days off. Any and all info will be greatly appreciated. I am wondering if I should just stay with verzenio. Am I stresses or what???

I am sorry that treatment failed. Have you discussed the next steps with your doctor?

This is odd . At Kaiser Perm , they have me on 21 days of Ibrance then 7 days off . I have been held up 3 WEEKS for low blood count the 1st cycle . Now, just past 2nd cycle, I am again prevented from continuing the Ibrance , Neutropenia again . Even on a lower dose (100) which I pushed for . So my R lung keeps filling up w liquid and I have to ck into the hopital and have it drained by Thoracentesis , so I think that sucks . I want a continuous treatment not this off and on crap , very frustrating . I would race to a different cancer dr , but stuck w Medicare assigned to Kaiser until OCT , when the whole freakin United States can do open enrollment, GRRR . I feel discouraged and trapped , and have no idea if this Ibrance/falsodex shots regimen is even worth continuing to try . It would be fine , not getting horrible side effects , considering my oncologist tried to shove me into Taxol drip chemo FOR THE REST OF MY LIFE . OH HELL NO . That would def be NO quality of Life and HUGE INTENSE side effects , vs the Ibrance pills and the monthly shots . Any guidance or ideas ?

This is odd . At Kaiser Perm , they have me on 21 days of Ibrance then 7 days off . I have been held up 3 WEEKS for low blood count the 1st cycle . Now, just past 2nd cycle, I am again prevented from continuing the Ibrance , Neutropenia again . Even on a lower dose (100) which I pushed for . So my R lung keeps filling up w liquid and I have to ck into the hopital and have it drained by Thoracentesis , so I think that sucks . I want a continuous treatment not this off and on crap , very frustrating . I would race to a different cancer dr , but stuck w Medicare assigned to Kaiser until OCT , when the whole freakin United States can do open enrollment, GRRR . I feel discouraged and trapped , and have no idea if this Ibrance/falsodex shots regimen is even worth continuing to try . It would be fine , not getting horrible side effects , considering my oncologist tried to shove me into Taxol drip chemo FOR THE REST OF MY LIFE . OH HELL NO . That would def be NO quality of Life and HUGE INTENSE side effects , vs the Ibrance pills and the monthly shots . Any guidance or ideas ?

I had neutropenia and liver issues with Ribociclib. What causes your lung to fill with fluid?

First off if you just don’t like the doctor then I would look on the website for your insurance and see if there is another provider in your area.
Failing that, I would check and see if there is a nurse coordinator/patient advocate you can talk to. I would also, have someone with me at my next appointment. Another person listening can be a big help, also some doctors will be more open to questions if you write them down and have someone with you.
I really hope you can talk about your treatment plan and what YOU would like out of that plan.
Do you have someone who can join you, and listen in, help ask questions?

I appreciate your ideas but have tried them already . I had my son & DIL , who both have MPH and also years of working in medical fields , and they are very frustrated now too . Having no clear treatment plan , and constant missteps and mistakes , are why I have now switched , new drs next week, fingers crossed I'll get some guidanceand real medical care . I was def trying to get away , as stated above , assigned medicare insur traps me for now. So beyond these suggestions, I am constantly being told to book my own appts , and guess when I need the next thoracentesis , etc . Filing a complaint gets you a form letter with a form apology , but no real change or accountability so far.

I appreciate your ideas but have tried them already . I had my son & DIL , who both have MPH and also years of working in medical fields , and they are very frustrated now too . Having no clear treatment plan , and constant missteps and mistakes , are why I have now switched , new drs next week, fingers crossed I'll get some guidanceand real medical care . I was def trying to get away , as stated above , assigned medicare insur traps me for now. So beyond these suggestions, I am constantly being told to book my own appts , and guess when I need the next thoracentesis , etc . Filing a complaint gets you a form letter with a form apology , but no real change or accountability so far.

The vague answer is " The cancer " which is dividing and residing in the pleural area , between lung and the ribs Supposed to be air in there, not liquid and it is horrible gasping for air , headaches , or trying to sleep , or just unloading a bag of groceries . No real answer has been given to me for that question . New doctors next week : pulmonologist and a new oncologist ! I'm excited and hopeful .

The vague answer is " The cancer " which is dividing and residing in the pleural area , between lung and the ribs Supposed to be air in there, not liquid and it is horrible gasping for air , headaches , or trying to sleep , or just unloading a bag of groceries . No real answer has been given to me for that question . New doctors next week : pulmonologist and a new oncologist ! I'm excited and hopeful .