Hi @dqg, I would like to invite @audriana to the conversation since she looked into these treatments as well. You can see her post here: Rejection letter from Janssen CarePath re Spravato: https://connect.mayoclinic.org/discussion/rejection-letter-from-janssen-carepath-re-spravato/

Here is some information you may like to browse.
A New Ketamine Nasal Spray Has Been Approved for Depression (But It’s Not for Everyone) - The possible benefits and risks, explained: https://health.clevelandclinic.org/a-new-ketamine-nasal-spray-has-been-approved-for-depression-but-its-not-for-everyone/

2019 - FDA-Approved Ketamine Nasal Spray Cuts Depression Symptoms in 24 Hours: https://www.healthline.com/health-news/ketamine-nasal-spray-can-help-reduce-depression-in-24-hours

What steered you to the ketamine treatments for depression? Are you currently on anything to manage?