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Concerned about the side effects of anastrozole

Breast Cancer | Last Active: Nov 21 7:48am | Replies (1935)
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@colleenyoung

Just for clarification
Faslodex (fulvestrant) is not technically speaking an aromatase inhibitor. It is also an anti-estrogen medication.but is an estrogen receptor downregulator (ERD). It works by blocking the actions of estrogen in the body.

Faslodex is used in postmenopausal women with hormone-related breast cancer that is advanced or has spread to other parts of the body (metastatic).

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Replies to "Just for clarification Faslodex (fulvestrant) is not technically speaking an aromatase inhibitor. It is also an..."
pjsfla | @pjsfla | Apr 29, 2022

I'm sorry if I mis spoke . I am MORE confused , however and request clarification on a "inhibitor" vs a "downregulator" of estrogen . Please ?

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adanab | @adanab | May 1, 2022

I'm curious how oncologists come up with their drug combinations, i.e., I was on Ibrance/Letrozole and when it stopped working was put on Faslodex (injected)/Afinitor. But I've seen Faslodex/Ibrance combos and many others. I wonder if it depends on the particular cancer (I'm mets BC) or is an institution or onco protocol, or? Can you shed any light on this? Thanks.

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