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Aromatase Inhibitors: Did you decide to go on them or not?

Breast Cancer | Last Active: May 12, 2023 | Replies (1190)
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@windyshores

@callalloo and others:
https://www.ncbi.nlm.nih.gov/books/NBK534771/#:~:text=The%20frequency%20of%20biphosphonate-induced%20osteonecrosis%20in%20osteoporosis%20is,is%20only%20slightly%20higher%20than%20in%20non-osteoporotic%20patients.?
The frequency of biphosphonate-induced osteonecrosis in osteoporosis is very low, ranging from 0.15% to less than 0.001% person-years of exposure, and is only slightly higher than in non-osteoporotic patients.

BUT 1% to 7% of breast cancer patients with bone metastasis, as explained in the study linked above

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Replies to "@callalloo and others: https://www.ncbi.nlm.nih.gov/books/NBK534771/#:~:text=The%20frequency%20of%20biphosphonate-induced%20osteonecrosis%20in%20osteoporosis%20is,is%20only%20slightly%20higher%20than%20in%20non-osteoporotic%20patients.? The frequency of biphosphonate-induced osteonecrosis in osteoporosis is very low, ranging from..."
callalloo | @callalloo | Apr 26, 2022

It is low with the caveat that it has only started being tracked recently. (Meaning people could have had in the past and had it attributed to poor oral care, age or just written off as an anomaly.)

I don't think people are sitting around choosing between risking osteoporosis or bone metastasis though. I'm sure that no one wants either one of them.

For me, personally, the myriad treatments for osteoporosis are so unpleasant that I am just motivated to do anything that I can to postpone ever needing them. And hope that far better preventative options become available. I look at young girls (and boys) and the ever-increasing subtle forms of eating disorders and worry about them a lot.

There a lot of Hobsons's choices in medicine unless we can be and remain perfectly healthy, alas.

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