Anyone with CKD & type 2 diabetes taking Farxiga (dapagliflozin)?

Posted by collegeprof @collegeprof, Apr 22, 2022

My endocrinologist suggested I take Farxiga to help with Type 2 diabetic issues and protect Stage 3B from becoming more serious. She is a great doc and follows the science of this drug. Several months after taking the drug, my outside of Mayo nephrologist back then questioned the validity of the drug. So I went to WebMD online, which is not a truly scientific source for information, say that Stage 3B should not be taking the drug, so I stopped last November without the good wishes of my endocrinologist. Fast forward to past February, I see a New Mayo nephrologist who strongly concurs with the usage of Farxiga with my endocrinologist. Both explain that it is the science that encourages them with CKD. When I stopped taking Farxiga, my GFR was 45 and 44 respectively. I restarted Farxiga around March 1st, and my latest GFR was 37. Granted I have had fluctuations in the past, but unsure of the future GFR direction. I will be tested again next week so I will have a better idea. In the meantime, are there any of you who have taken Farxiga and can share your results as it relates to CKD? I know some have talked a little as it affects heart problems or side effects, but I saw very little on this forum with CKD.

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@collegeprof, I'm tagging a few other members like @lyssia @jkluv7 @tcokeefe and @imhart, who have mentioned Farxiga (dapagliflozin), a medication for adults with type 2 diabetes, heart failure with symptoms, and chronic kidney disease (CKD). I hope they have some experiences and insights to share with you.

GFR, as you pointed out, can fluctuate, so it may be too early to pin your decision on the most recent reading. I encourage you to share your concerns with your Mayo nephrologist without hesitation. When is your next GFR?

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@colleenyoung

@collegeprof, I'm tagging a few other members like @lyssia @jkluv7 @tcokeefe and @imhart, who have mentioned Farxiga (dapagliflozin), a medication for adults with type 2 diabetes, heart failure with symptoms, and chronic kidney disease (CKD). I hope they have some experiences and insights to share with you.

GFR, as you pointed out, can fluctuate, so it may be too early to pin your decision on the most recent reading. I encourage you to share your concerns with your Mayo nephrologist without hesitation. When is your next GFR?

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@collegeprof I have taken Farxiga for several years now and have had no issues with it. I do not have CKD so can not give any insight for that. Best Wishes Alyssia

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@colleenyoung

@collegeprof, I'm tagging a few other members like @lyssia @jkluv7 @tcokeefe and @imhart, who have mentioned Farxiga (dapagliflozin), a medication for adults with type 2 diabetes, heart failure with symptoms, and chronic kidney disease (CKD). I hope they have some experiences and insights to share with you.

GFR, as you pointed out, can fluctuate, so it may be too early to pin your decision on the most recent reading. I encourage you to share your concerns with your Mayo nephrologist without hesitation. When is your next GFR?

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Not enough can be said about Mayo's patient portal. It is by far the best interactive patient care portal I have ever experienced. I contacted my Mayo nephrologist about my concern of Farxiga. He literally answered me on the portal within an hour and set me up for another blood test as my oxygen level was lower than expected. Another test was made, and the results were published on my portal in less than one hour. He concluded Farxiga was safe as my oxygen level was normal in the new test, all in a couple of hours. My next appointment for a blood test result with my endocrinologist is in 11 days.

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@lyssia

@collegeprof I have taken Farxiga for several years now and have had no issues with it. I do not have CKD so can not give any insight for that. Best Wishes Alyssia

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Thank you so much!

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I went on 5mg Farxiga two months ago. My GFR went from 29 to 26, but my local nephrologist said that at the beginning, it is expected to drop. He is not worried. Over the long haul, it should go up more than if I didn’t take it.🤞

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@lisacohen1952

I went on 5mg Farxiga two months ago. My GFR went from 29 to 26, but my local nephrologist said that at the beginning, it is expected to drop. He is not worried. Over the long haul, it should go up more than if I didn’t take it.🤞

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PS. Mayo nephrologist is on board too.

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@lisacohen1952

I went on 5mg Farxiga two months ago. My GFR went from 29 to 26, but my local nephrologist said that at the beginning, it is expected to drop. He is not worried. Over the long haul, it should go up more than if I didn’t take it.🤞

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This is good to know. Thank you.

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The side effects of this drug are awful, according to the FDA website. The warnings on this drug have been a lot. This drug is touted to lower A1C. This is exactly what can be done with a low carb diet and a bit of exercise.
https://www.accessdata.fda.gov/scripts/cder/safetylabelingchanges/index.cfm?event=searchdetail.page&DrugNameID=105

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@jkluv7

The side effects of this drug are awful, according to the FDA website. The warnings on this drug have been a lot. This drug is touted to lower A1C. This is exactly what can be done with a low carb diet and a bit of exercise.
https://www.accessdata.fda.gov/scripts/cder/safetylabelingchanges/index.cfm?event=searchdetail.page&DrugNameID=105

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Thank you for your input.

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