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@callalloo

There are two numbers you receive from the OncotypeDX. The "Recurrence Score Result (RS) and the "Distant Recurrence Risk at 9 Years." So I'm guessing that, in your case, the former is 13 and the latter is 4%? [My numbers were 9 and 3, respectively. The risk number is derived from the RS by some OncotypeDX algorithm but is not a linear, direct calculation from what they told me.]

That's good news and I hope it provides a bit of comfort. You might decide to 'throw everything at" the remaining cancer risk, or not, but take comfort that that cancer doesn't put you squarely in the country-wide risk with people who might have comorbities or negative lifestyle factors that you know don't apply to you.

I found the OncotypeDX test very helpful. For one thing, even if I took anti-hormone therapy drugs, I'd still have the remaining 3% risk in theory. I decided that the additional 2 percentage points of "no drugs and 5%" was my path. And if the cancer does recur, I'll know it had a 3% chance even if I had taken the anastrozole. Cancer is like a lot of situations in life where there are no perfect decisions except, maybe, in hindsight.

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Replies to "There are two numbers you receive from the OncotypeDX. The "Recurrence Score Result (RS) and the..."

The Breast Cancer Index and Prosigna Assay consider 5% to be "high risk." The Oncotype considers it low risk. So even at this basic level, decisions are confusing. It is good to remember that with hormonal cancers, risk continues to increase over the years. @jaynep my score was 8, and I did 5 years of Femara, with few problems. Someone else might make a different decision. My own view is that it is good to try a med before declining, because many do not have side effects that are troublesome.

Thanks for your input. It is all so confusing and you helped me to understand a bit. I’m leaning toward trying anti hormone therapy but I don’t want to continue if it causes living in misery. Thanks again, it helps hearing from others dealing with the same situation.