First of all, I want to send a hug out to you and let you know you are not alone and surrounded by so many women who are and have gone through this. I will be praying for healing for you on 4/29. I've just marked it on my calendar. You'd be surprised how prayer works. Well, it was a very personal experience for me with the Radiation, my numbers were low, but of course my surgeon encouraged me to go see the Radiologist, which I did. But what really changed my mind was I was not going against science or what may indeed be a good and recommended treatment, I really studied about it and with what I've seen in other women after the treatments, something said not to actively pursue it. Again, my numbers were low, less that 9% so I opted not too. Please listen to your doctor and look at your own situation, and you will make the best decision for you. I have been on Anastrozole for almost 3 years and I am a active 63 yr old woman, and I have had a bit of tiredness at the beginning, but no other side effects. My oncologist says I should be a poster child for Anastrozole. But because I am still working so much I really don't have time to think about any aches or pain, I'm of the mindset, mind over matter, but stay active, exercise and eat right, and get good sleep if you can. Please let me know how your appointment goes and I will be thinking and praying for wonderful things to happen. Love and Life