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Psych meds, weight gain and metformin

Depression & Anxiety | Last Active: Aug 17, 2022 | Replies (17)

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@amandaa

Hi @mcgrathj and welcome to Mayo Clinic Connect. This is very interesting. I have not heard of adding metformin to psych meds, but with what you have described it is pretty sound logic. I do know that there is a slight chance of experiencing confusion while on that medication.
Have you started metformin already or are you just discussing with your doctor?

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Replies to "Hi @mcgrathj and welcome to Mayo Clinic Connect. This is very interesting. I have not heard..."

Hi @amandaburnett, thanks for the welcome. I have not begun metformin yet as I'm awaiting blood tests but I am discussing this with my GP. My psychiatrist is pretty old school and won't try anything novel until it appears in the CANMAT guidelines. :(. Metformin and liraglutide has been studied primarily with antipsychotic-induced weight gain, yet as I mentioned it is being looked at for repurposing as an "antidepressant". It has a favorable safety profile. I don't know much about the med, so I haven't heard about confusion. I'm definitely interested in other people's experience with this med. Thanks for responding. Just curious, are you a medical professional?