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@callalloo

Exactly! This is totally wrong.. Breastcancer.org is still saying, which is completely flat out incorrect, that the OncotypeDX can yield ANY info upon which to help base a radiation decision.

Oncotype doesn't have a test that addresses radiatiion. Yet, according to the senior science guy I talked to, doctors and patients are seeing this misstatement of fact and thinking it's true. The OncotypeDX is strictly designed to yield a 'likely benefit versus risk' anslysis of chemo for the person whose 21 genes the test looked at.

Virtually zero inferences can be drawn about radiation benefits for that specific person from the OncotypeDX. [There is also an Oncotype Breast Cancer Assay, which doesn't address chemo or radiation either.]

I've written to Breastcancer.org several times to correct their misunderstanding to no avail. The problem with mistruths on the internet is that they have a very long shelf life. It's impossible to get them off of the zillion other websites that just cut-and-paste stuff to their own.

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Replies to "Exactly! This is totally wrong.. Breastcancer.org is still saying, which is completely flat out incorrect, that..."

I am trying to understand. Oncotype does two things: assesses risk of distant recurrence, and benefit of chemo. So if risk is low wouldn't that help a patient decide not to have radiation>

I think it is different for mastectomy patients, many of whom do not have radiation. This was my biggest decision. I was told that one in five radiologists would suggest radiation for me, and my tumor board said no.. My low Oncotype (and assumed low recurrence risk at that time) definitely affected my decision not to have radiation.