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Aromatose inhibitors and osteonecrosis of the jaw

Breast Cancer | Last Active: Apr 10, 2022 | Replies (6)
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@sandyjr

https://pubmed.ncbi.nlm.nih.gov/32270377/ right now I am ok. I do not take biophosphates. I have friends that got this from taking arimatose inhibitors and therefore I am curious if symptoms/problems are evident early on.

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Replies to "Https://pubmed.ncbi.nlm.nih.gov/32270377/ right now I am ok. I do not take biophosphates. I have friends that got..."
Chris, Volunteer Mentor | @auntieoakley | Apr 10, 2022

The folks who published this paper concluded that it was a false positive, and that the algorithm was picking them up because of the bisphosphonates being given in conjunction with the AI. It was in the paper just further down and hidden a bunch of medical lingo. I hope this eases your concerns.

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callalloo | @callalloo | Apr 10, 2022

I looked at the article you linked and it says that the signal associating the three aromatase inhibitors was a 'false positive.' Meaning there us no direct link between the drugs and ONJ. If I understood that you gave friends with the condition, and taking AIs, it's likely they were also taking bisphosphonates as an auxiliary drug.

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