Glad that you're less worried about the radiation. Anastrozole and the other aromatase inhibitors have some side effects, the one that is pretty much a given is accelerated loss of bone density from the depletion of estrogen in the body. The actual rate acceleration differs among people due to body chemistry, age, existing bone density and other factors. I'd try to get a DEXA scan if you don't have a current one so you have a baseline pre-anastrozole picture to measure future DEXA scans against. And be prepared to explore drugs to prevent or treat osteoporosis if that is an issue. (That might sound onerous but the regrets of people who weren't adequately informed about anti-osteoporosis strategies when on aromatase inhibitors is a major cautionary tale. I'd also tell my cardiologist so s/he will keep a more-frequent watch for any change in cholesterol levels at a minimum. I regret if that sounds discouraging buy tamoxifen is harder on the body (risk of DVT and related cardiac events) so anastrozole is a gentler drug in many ways though be prepared for some arthaligia. If you don't encounter it, great.