@acb I'm sorry that your mom was not able to get an appointment. I have heard that Mayo gets a lot of people applying about neuropathy and general medicine. It may help if you can start with a specialist for a specific problem instead of a general application. I was accepted at Mayo for spine surgery. I had been turned down by 5 local (non Mayo) surgeons and my case had some unusual symptoms that were being missed, so that did help me get into Mayo as a surgical patient. I referred myself. Sometimes your own doctor can help refer a patient to Mayo. There are also doctors trained at Mayo practicing elsewhere, and there is a Mayo Clinic Care Network where specialists have a relationship with consulting Mayo Clinic specialists while providing care at other hospitals nationwide.

MAYO CLINIC CARE NETWORK
https://www.mayoclinic.org/about-mayo-clinic/care-network/network-members
The Mayo Clinic Care Network helps keep care local by providing guidance and answers to many questions that might otherwise require a referral to a specialist. In many cases, this spares patients the expense and inconvenience of additional appointments and unnecessary travel. If specialty care is needed, patients can be seen by local providers or referred to Mayo Clinic. If you scroll this page down there is a member map on the left side.

I have also heard that Cleveland Clinic is similar to Mayo is expertise and patient care. I would have contacted them if it didn't work out at Mayo. Would she be willing to try applying to one of the other Mayo campuses? There are 3 campus locations, Rochester, MN, Jacksonville, FL, and Phoenix, AZ.

Can you share specifically what type of care your mom is looking for?