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@callalloo

Alas, I don't see a differentiation between local disant recurrence and spread. The senior member of the science team at Oncotype told me they tend to think the risk score covers both IF the tumor margins were adequate and clean but their legal counsel recommends against making such a statement. I think it's interesting that they also discover undiagnosed invasive cancers sometimes. The cells behave differently when tested and they've had to notify doctors to re-examine the patient and rethink recommendations for treatment. Talking to the people at Oncotype was very informative and welcome.

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Replies to "Alas, I don't see a differentiation between local disant recurrence and spread. The senior member of..."

I talked to them a lot in 2015 when I was diagnosed. With grade 3, high ki67%, lymphovascular invasion, and ambiguous HER2 (only definitely negative in one out of 4 tests), I was troubled by doctors' reliance on the (newish) Oncotype but would have struggled with chemo. And my cancer was highly hormone-positive. Now, 7 years later, even treatment for metastasis avoids chemo as much as or as long as possible when ER+.