← Return to Aromatase Inhibitors: Did you decide to go on them or not?

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@gillooly

Thank you for the reply - it is helpful and restored hope. The Onco recurrence score was 16; the distant recurrence risk at 9 years with AI therapy is 4%. Quantitative Single- Gene Scores : 11.7 ER Positive; 5.5 PR Positive and 8.8 HER2 Negative. I had a lobular carcinoma with no lymph node involvement My surgeon rated the cancer as Grade 2 with a 5-year survival of 93%. The oncologist used a letter grading system rather than numerical; his grade was 1A or 1B. No lymphovascular invasion. The numbers on my Onco report do not seem to be helpful in predicting outcomes without the aromatase inhibitors. Tomorrow I will visit the website for clarification on the numbers. I appreciate your input. It has been very helpful and motivational.

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Replies to "Thank you for the reply - it is helpful and restored hope. The Onco recurrence score..."

My oncologist(s) and endocrinologist cite the breast cancer industry thinking that aromatase inhibitors can reduce the risk of recurrence by approximately 45%. With that current thinking, your risk of recurrence if you do not take them is approximately 6.5% if the OncotypeDX score is valid. (My doctors think it is.) I don't know if that helps but gives you a "if I don't take aromatase inhiibitors" framework. Oncotype's customer support is very good and can describe more.