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DiscussionAromatase Inhibitors: Did you decide to go on them or not?
Breast Cancer | Last Active: May 12, 2023 | Replies (1190)Comment receiving replies
Replies to "I have been on Anastrozle for 6 months and was congratulating myself on lack of significant..."
I'm so sorry to read about what you're going through. I chose not to take an aromatase inhibitor in part because I have the genetic marker for, and a nuclear family full of, heart disease. However, I question you doctor's thinking that a static could not work. My former (great) cardiologist invented the calcium store and has patients in their 90s who had their first heart attack in their thirties and are alive and active today. Please do search out some more proactive physicians. I had to do it after moving to a new area but it was worth it. I've had high cholesterol for a zillion years but the echocardiagram of someone decades younger. And I cannot take statins. The human body is complicated and fascinating and isolating a variable here and another there does not tell the whole story. Best wishes in getting a new medical team to work with you.
Do you mean your Oncotype score was 4 with anastrazole? So the score itself was 8? That is a very low score, relatively low risk. What was the grade of your cancer, and any lymph nodes positive, or lymphovascular invasion?
That is quite a list of possible side effects. I believe the lipid rise is a known side effect. Do you think there are any other possible explanations for other side effects? Blood pressure is very variable anyway...
I wonder if you could switch to Femara, or switch brands, or take a half dose or alternate days. The package insert for Femara cites a study showing that 20% of the recommended dose is effective. My doc okayed a half dose (alternate days) but I stayed on a full dose.
I hope the monitoring is helpful. Regardless of cause, your symptoms sound scary and monitors are sometimes reassuring and in any case will tell you what is going on.