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Rising PSA years after radical prostatectomy

Prostate Cancer | Last Active: Mar 5 7:14am | Replies (206)
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@jrp

I just got my results of rising PSA. I had a Radical Prostatectomy in June 2019. My PSAs were .001, then .009, again.009, and now have jumped to .77. We are obviously upset Doctor says we can take another test in 10 weeks followed by a pet scan. I am hoping my medications to be a cause of this rise as I just stated Hydrochlorothiazide 25mg and Oxybutynin Chloride Er for symptoms. Thoughts?

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Replies to "I just got my results of rising PSA. I had a Radical Prostatectomy in June 2019...."
Colleen Young, Connect Director | @colleenyoung | Mar 20, 2022

Welcome, @jrp. I can imagine you are alarmed. There can be a number of things that contribute to a rise in PSA. I wrote more about it earlier in this discussion. You can jump to my comment here: https://connect.mayoclinic.org/comment/335976/

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natem | @natem | Mar 24, 2022

I was told by my medical team .2 was generally considered recurrence. Mine rose to that and I'm getting radiation presently. I waited approx 6 weeks and it rose to .3!

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jrp | @jrp | Mar 28, 2022

I might add that I had 39 rp right after surgery. I found that I had radiation cystitis afterward and as I was on eliquis for Afib i ended up getting a watchman device in my heart to stop the bladder bleeding. It kind of worked as ThE bleeding has stopped. Right after the prostatectomy the nurse was irrigating my Foley bag on The wrong side and it ended up blowing up inside my bladder. It took a long time to get this settled out and it made it so I had a very hard time holding my urine during radiation. This whole thing has been a crazy mess for me.

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james1951 | @james1951 | Apr 6, 2022

To me that doesn’t seem to make sense retest and see what that is.

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