Thank you. I think that it is interstitial cystitis. My doctor wanted to prescribe me another antibiotic, and I opted out of taking it. He said if THAT didn't work, that I should go see a urologist. I decided to do get off of my prescriptions (birth control and concerta) and do a cleanse for a week. I pretty much had immediate relief and didn't notice a flare up until I had a couple glasses of wine a couple weeks later. I tried wine again a week or so later, and had the pain/pressure again. So, I've come to the conclusion that wine causes it to flare up. Maybe it is the tannins or the chemicals (from the grapes). Obviously, this is an unprofessional diagnosis that I made--but I haven't had any issues for the last month or so. I also work with a retired nurse that recommended taking sea buckthorn on a regular basis, so maybe that is helping too. Thanks for your input.