That must have been so discouraging, @mzamyl. We just witness our lives getting smaller and smaller, so limited by pain and lack of energy. When I looked in the mirror, I looked like death warmed over. Before I was diagnosed with PMR, I had anemia, which made me very tired and Shingles, even after having the Shingrex vaccine. I was lucky to have a close friend, an infectious disease specialist, take an interest, review my labs, and tell me what tests to ask my PCP to order. He was really resistant, but I pushed him. My inflammation markers were off the charts, then, I started prednisone and had a temporal artery biopsy within a week. I wish you the best.