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Starting radiation & hormone tx for recurrence: Your experience?
Prostate Cancer | Last Active: Jul 23, 2022 | Replies (26)Comment receiving replies
IAs the attached chart shows, I had BCR though 18 months after surgery, not nine years. If you decide to do the recommended treatment, it is fairly standard treatment now, IMRT to the prostate bed and six months of ADT. Some will include the pelvic lymph nodes because of micro-metastatic PCa.
If you do the six months ADT, ask your medical team about - https://www.pcf.org/news/breaking-news-fda-approves-first-oral-hormone-therapy-for-advanced-prostate-cancer/ It's CV and metabolic SE profile are lower than Lupron, it does not have the flare Lupron does and recovery of testosterone is faster. the zeroing out of your testosterone will have SEs, you can research all the possible ones though like statistics and the bell curve, average, mean, mode...your experience may be different. For the 18 months I was on Lupron, hot flashes, genitalia shrinkage, muscle and joint stiffness, weight gain (even with exercising and watching my diet), and mild fatigue.
Two things to keep in mind, with recurrence, generally the earlier and the lower the PSA, the better the chance of either an elusive "cure" or long progression free survival. Combination therapy is generally better than monotherapy.
As you can see from my chart, I had radiation twice, the prostate bed and the PLNs. I had no SE then nor now, testimony to the technology and skill of my radiation team. If you elect to do the treatment, your radiologist should show you the treatment plan using the planning software (which is 3D). You'll be amazed. They should include boosts to any sites identified in the scan and wider margins around them.
Replies to "IAs the attached chart shows, I had BCR though 18 months after surgery, not nine years...."
May I ask, how were you able, or what brought your psa down when it rose to .29 Jan 21, 2021 and .3 on May 1, 2021? Best wishes for your continued success. Kind regards, Nate
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Thanks very much! Fortunately, that's what my Radiation Oncologist prescribed. I've had a pacemaker in since I was 45. So this having a lower cardiac profile helped it get approved. Sounded odd though, like he might have to fight my insurance company. Maybe they're not all covering it, because until I mentioned heart, I think he was going to give the injection. I'm surprised, he's at JHH , would've thought that would be the new standard of care.
A shortcoming of mine is I'm not always wanting to see the details, but he did show me the PSMA PET Scan, showing me the type 3 image at the and of the lymph nodes, further where the prostrate was, such the he bent, or drew the scan for the Versa radiation machine to include it. But, I haven't asked all the details about radiation dosage. it seems i receive two treatments that once started, only take about a minute each. The machine scans me first every time. I see you've been at NIH, I'm not more than about 45 minutes away. Thank you again for sharing that. Is there a specific need the fulfilled that may be unique and, or beneficial? It appears you have had much activity with testing, imaging and treatment. I'm 61 y.o. and self employed real estate sales, hoping I may remain active while treating, surviving,. I hadn't had any symptoms, but the .2 and .3 psa's I just started the Orgovyx about 2 or 3 weeks ago. It's fast working and I'm anticipating genital shrinking as I think it does the same thing as Lupron. So, I don't know if this will cure it even though that's the stated goal. I was hoping to put off ADT for as long as possible after completion of 6 month regimen. I'm sure that's never been said before...
Another concern is if it has micromastasticized and I need hormone therapies, I fear for when they become ineffective. I am going to ask him about boosting the site and wider margins around it. Thanks very much. My best wishes to you!
Kind regards,
Nate