I'll admit that at Stage IIIc (5 tumors and 10 out of 16 nodes positive) I didn't have much choice. Nevertheless, I was extremely fortunate throughout heavy chemo and full radiation -- I found all of it extremely tolerable (except for losing my hair, of course) Once that course of treatment was over, I sought guidance at a nearby cancer center. They prescribed 2 year Tamoxifen (I was 69 at the time) and then 8 years AI (currently doing). I also was prescribed 3 yrs. Zometa infusions every 6 months. That's probably the worst decision, as I have dental problems and have to live with them for the moment. I am not aware of any side effects from the AI (Anastrozole) My feeling is I will do whatever I can to fight off distant mets. I would add that I consider the maintenance part of the treatment to be the most important decision to make. Get second opinions (and third) if you feel your oncologist is offering a "cookie cutter" regimen. Every person is different; why we all have to do our own solid research based on our type of cancer and our general health situation. Such a personal decision: all of this. Blessings and peace to everyone faced with making these maintenance treatment decisions. They are important.