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Alternative to Prednisone for Treating PMR?

Polymyalgia Rheumatica (PMR) | Last Active: Aug 25, 2023 | Replies (68)
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@naparker

Hi, kvd9. Maybe someone's already mentioned Methotrexate as an alternative to Prednisone. Methotrexate is most often prescribed with folic acid. I finally got an appointment to see a Rheumatologist for my PMR, scheduled for this afternoon, and I plan to ask about Methotrexate as an alternative. Good luck to you.

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Replies to "Hi, kvd9. Maybe someone's already mentioned Methotrexate as an alternative to Prednisone. Methotrexate is most often..."
kmeikle1 | @kmeikle1 | Mar 8, 2022

Mehtotrexate is not an alternative to prednisone. It can be used for polymyalgia rheumatica as a steroid sparer. So for some people having difficulty tapering, methotrexate may help alongside prednisone. Effectiveness data of methotrexate for PMR as a steroid sparer is questionable, and there are possible side-effects .

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