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@crlwks269

I have been taking duloxetine 20mg a day now for neuropathic/ muscular upper back pain that I have had for 4 years and it really seems to be helping. I have tried gabapentin and Prozac on the past as well as cbd and the duloxetine has helped the most. I wish I had tried it sooner. Side effects have been insomnia and constipation which I hope will eventually go away. Hope this helps.

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Replies to "I have been taking duloxetine 20mg a day now for neuropathic/ muscular upper back pain that..."

Hello @crlwks269 and welcome to Mayo Clinic Connect. I'm so glad that you joined this discussion about Duloxetine. It is so good to find something that works, isn't it?

Side effects are very common with most meds. I suppose we all need to weigh the side effects versus the positive impact that they have on our feeling of health and discomfort.

I look forward to getting to know you better. As this is your first post on Connect, would be comfortable sharing a bit more about your neuropathic/ muscular upper back pain?

You did not mention if you are also taking hydrocodone but that class of drug can cause constipation.