Albuterol is a beta agonist, metoprolol a beta blocker. So my 2 meds were working against one another, neither doing what was intended.

I am neither a doctor nor pharmacist, so I cannot tell you what the difference is between the actions of the 2 types of drugs.

There have been people on Connect treated with Arikayce after being unable to tolerate the Big 3, but maybe they can tell you how successful it was.
Sue