Hi. I didn't take bioidentical hormones, so I can't comment on that. However, I have been on anastrozole since November 2021 as well and I seem to be having similar side effects as you. I'm tolerating hot flashes ok, but the tears sure do flow at the drop of a hat. That didn't happen to me before. I didn't think my diagnosis was bothering me. It's my second breast cancer diagnosis and I really feel like I'm ok with it. But, I still wonder if I'm not as ok as I think OR if it is the drop in hormones that is causing this sadness. I still don't know for sure, but I can relate to what you are feeling. Hugs.