Welcome @12cmgc, You ask a good question. Here's what I've found out -- "Is vitamin B6 deficiency genetic?
In addition, vitamin B6 deficiency can result from malabsorption syndromes, such as celiac disease, Crohn's disease, and ulcerative colitis. Certain genetic diseases, such as homocystinuria, can also cause vitamin B6 deficiency [2]. Some medications, such as antiepileptic drugs, can lead to deficiency over time." --- Vitamin B6 - Health Professional Fact Sheet: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

Here's another reference that I think reads a little easier. - How Genes Influence Your Vitamin B6 Requirements: https://www.xcode.life/genes-and-nutrition/genes-vitamin-b6-requirements/

Have you been diagnosed with any condition related to B6 levels?