Currently stepping down on prednisone from 40mg -- down to 5mg and my RA doctor put me on 2.5mg of Methotrexate / 6 tablets every 7 days. She wants to prednisone gone ----- so far -- so good ---- I go back to the RA doctor first of april ---- since the PMR flare up and the heavy dosage of 40 mg of prednisone -- I have lost all interest in other activities -- example, converting a attached garage to a living area - lost all interest --- my hips and knees are in alot of pain ------ so ------------ I hope, hope this all goes away and I can't back to 100% function