Sue, thank you for your comments and important information. The steroids and Levaquin are for the Bronchiectasis. I imagine if I go on the Big 3 he would take me off the Levaquin. I take Simponi (biologic) IV every 8 weeks for my RA. I don't think the lung biopsy did a colony count nor a sensitivity. He is not working with an infectious disease specialist. My pulmonologist says he has treated others and that they've done well. And no I didn't ask why I would have to take daily. Thanks for the information. I may try and go to Mayo in Jacksonville.