It almost brought me to tears reading your story. I am so glad you had 24 years in between. I also went through this when I started endocrine therapy. My radiation doctor started me on some sertraline at that time and I am on it still today. Just like pregnancy or menopause, when you mess with the hormones it can turn on the faucets. A possible answer is both, anastrozole and breast cancer. Are you comfortable talking to your doctor about this?