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@alexmemphis

Colleen,
Since there seems to be a possible connection between the Covid vaccine and PMR flares, I wonder if there is anyone doing research on this? I would gladly share my journey and I expect others would also. I see the challenge being how to create a situation in which the vaccine can be modified so that it doesn’t cause a flare. I understand that there have probably not been enough PMR flare cases to make it financially viable for drug companies to do the research. But perhaps if the Mayo immunization research group knew that there were several people with flares, it would make since to research it. I think Duke may have received a grant to study some PMR aspects also. I do want to get a booster and help protect myself and others from Covid, but am reluctant because I fear that a booster may cause another PMR flare. And PMR was very painful and significantly limited my daily activities. I would appreciate it if you could direct me to any related research studies. Thank you for all that you and Mayo do. This group is so helpful!

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Replies to "Colleen, Since there seems to be a possible connection between the Covid vaccine and PMR flares,..."

Alex, the relationship between autoimmune diseases and vaccination is a topic that researchers have studied in the past and likely continue to study closely with the global vaccination efforts to control COVID.

Here are a couple of past studies:
- Vaccination and autoimmune disease: what is the evidence? (2003) https://www.thelancet.com/pb-assets/Lancet/extras/02art9340web.pdf
- Vaccination and Induction of Autoimmune Diseases (2015) https://pubmed.ncbi.nlm.nih.gov/26728772/
- Vaccinations and Autoimmune Diseases (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402446/

To find clinical trials that are currently recruiting participants, you can search the national database or Mayo Clinic's clinical trials database:
https://clinicaltrials.gov/ct2/home
https://www.mayo.edu/research/clinical-trials
Sometimes your physician may know about clinical trials that are not yet included in the databases. I applaud you for being willing to contribute to research.