Anyone taken Evenity (romosozumab) for Osteoporosis?

Contraindicated with a vascular necrosis

Vascular necrosis or avascular necrosis? From radiation?

A vascular necrosis, also called osteo necrosis…high level steroid induced problem in the course of cancer treatment

The term is avascular necrosis, all one word. There is also a condition called vascular necrosis. How does avascular necrosis relate to Tymlos but not Evenity? I am curious. I undertand growing necrotic bone could be an issue but Evenity also grows bone so wondering the difference. Don't want to be a pain but if you have time...

No pain…Yes, you are correct.,..it is avascular necrosis..spell check problem. I do not recall the specifics, but was told I was not a candidate for Tymlos. Necrosis cannot be reversed..and could not tell you how the mechanics of Evenity would work in terms of the AVN effected bone. Good question.

I posted a reply in a new discussion/thread: https://connect.mayoclinic.org/discussion/exercise-to-strengthen-bones-for-osteoporosis/

(I did not want to reply on this thread, since the subject of this thread is Evenity)

Hello Windyshores -- Can you provide more information about the protocol for low dose Reclast?

Thank you everyone for this forum. It means a lot for me and I hope my experience might help but I apologize because English is not my mother tongue. I am starting Evenity next week in Switzerland after long hesitations. I discarded Forteo because I wasn’t ready for daily injections. I am 64. My T score is -4,6 for my spine. I had fractures since I was 14.

I am not sure what you mean by your question on low dose Reclast protocol. I am currently on Tymlos. My doctor knows I am very sensitive to meds. After Tymlos he thinks I may only need a maintenance dose of Reclast and may even be able to go on and off of it. So he mentioned doing 1/4 dose. I would drink a lot of water, take tylenol and they would infuse very slowly. He would monitor my bone density/loss and adjust treatment accordingly. This all depends on my results after one year of Tymlos. I may continue on Tymlos, or Forteo (which can currently be taken longer) or add Evenity if my osteoporosis is still severe.

Saz, hope you will continue to post as you begin Evenity. I should be a month or so behind you. Really hope it will help you... have you discussed with your doctor what to follow up with yet?