@wv54 -It is necessary and important to take Folic Acid the other six days of the week because Methotrexate affects your red blood cell count - or something to that effect. I took 5mg. Folic Acid a day.

I was on Methotrexate and Folic Acid for my psoriasis and it worked great - cleared it all - but unfortunately I was not allowed to stay on it long term because I have Fatty Liver Disease and Methotrexate can have an adverse effect if taken long term.