Welcome @davelobb12, Sorry to hear your neuropathy pain is getting much worse now after 3 years. The only fairly new one I'm aware of that shows some promise is the clinical trial for WST-057 (4% pirenzepine free base monohydrate) from WinSanTor.
"Treating Peripheral Neuropathy
The hope is that these new findings support the potential for select anti-muscarinic drugs already on the market, like pirenzepine, to be repurposed as a possible preventative, and even treatment, for the clinical effects of peripheral neuropathy, which, for patients, has been largely been a matter of pain relief, and associated with significant health care costs." — Blocking Anti-Muscarinic Drugs May Reverse PN: https://winsantor.com/anti-muscarinic-drugs-may-reverse-peripheral-neuropathy/
WinSanTor’s lead compound, "Treating Peripheral Neuropathy
The hope is that these new findings support the potential for select anti-muscarinic drugs already on the market, like pirenzepine, to be repurposed as a possible preventative, and even treatment, for the clinical effects of peripheral neuropathy, which, for patients, has been largely been a matter of pain relief, and associated with significant health care costs." — Blocking Anti-Muscarinic Drugs May Reverse PN: https://winsantor.com/anti-muscarinic-drugs-may-reverse-peripheral-neuropathy/
WinSanTor’s lead compound, WST-057 is the topical containing pirenzepene – https://winsantor.com/pipeline/
More info on the Phase 2 clinical trial page – https://clinicaltrials.gov/ct2/show/NCT04005287 is the topical containing pirenzepene – https://winsantor.com/pipeline/
More info on the Phase 2 clinical trial page – https://clinicaltrials.gov/ct2/show/NCT04005287
Have you made any lifestyle or diet related changes to see if they might provide a little relief?
Yes all the usual suspects like Vit B and Alpha Lipoic Acid…I swim to get some exercise but getting harder to walk as time goes on. THC helps me sleep at night but I need relief during the day. Very discouraging!