Given what you describe as to your health situation, the six months of ADT may be challenging whichever drug you use. The side affects are generally the same.
Here's a link which may show you are making the right decision- https://www.practiceupdate.com/c/131474/2/3/
I would ask your medical team about using Orgovyx, my medical team has never talked about it being used only in high risk, they use it in patients like you with other health risk factors because of the reason I listed.
As to the advice about exercising to mitigate the side affects,, not sure thee, perhaps your medical team can consider a physical therapist who can design a specific program for you?
Sorry to hear about your wife, it's not how any of want the "to death do we part" portion of our vows to go.
Kevin
Thanks for the link and the suggestions. Every bit of information is helpful.