Dear windyshores, Thank you for your information. I really appreciate your response. I too am very sensitive to medications and I have refused to take any of the osteoporosis drugs even though my endocrinologist has told me he felt it was necessary five years ago. I am also, now very concerned because my allergist just told me to not take any COVID booster while I am on Prolia. This is so frustrating since I clearly asked all of my doctors to address the warning to get permission from your doctor before getting vaccinated while on Prolia. Each of them said don't worry about that ! You will be fine. Unfortunately my allergist said I would be fine as long as I waited 6 weeks after Prolia to get the booster. Now, he is saying it is not Ok to get the booster. I did get the booster in November because that was six weeks after the last Prolia injection. If we need another booster, I don't know what I will be able to do. I ask all of my doctors "What is the Risk vs the Benefit ?" of any medication and "Would they tell their Mother to take this drug?" I figure that should protect me. Obviously, I was wrong. Please continue to connect with me and pass on any more wisdom you have. I really like the "ramping up of doses" that you are experiencing. No one suggested this approach to me. I will continue to update you on my journey to figure this out.