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New Daily Persistent Headache

Chronic Pain | Last Active: Mar 27, 2023 | Replies (140)

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@dhramsey

Here is my current NDPH cocktail in Buckets : this has my pain at a 4 and I work full time

Nerve Bucket
Duloxetine 60mg 1x per day
Botox - 90 days

Blood Pressure Bucket
Carvedilol 12.5mg.2x per day
Candesartan 16 mg tablet 2x per month

Acute Headache Bucket
Rizatriptan 10 mg disintegrating tablet (10 per month)

Preventative Headache Bucket
Galcanezumab-gnlm 120 mg/mL Pnij injection (Emgality)
zonisamide 100 mg capsule 1x per day

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Replies to "Here is my current NDPH cocktail in Buckets : this has my pain at a 4..."

This is very helpful. Thank you @dhramsey for sharing. We now have a list of other medications to try.

Wow, that’s quite the line up of meds. Interesting enough, I’ve arrived at something similar but less complete.
I was prescribed venlafaxine instead of cymbalta. I had to quit it pretty quickly because it caused extreme insomnia. Do you feel like the cymbalta is an important factor? It’s pretty similar to venlafaxine, so I was debating trying it and risking the same side effects. But if it is really providing you with significant relief, it may be worth revisiting.
About the blood pressure bucket: what is your normal BP? And I have been afraid of trying any beta blockers because I already have symptomatic low BP. What are your thoughts on these meds in particular?
For me, rizatriptan might as well be a tic tac. It has no effect at all. I do take tizinadine and cannabis to sleep during bad spells. I usually live around a 4-5 but I get attacks that last a couple of weeks at a time that go up to 8-9.
Topiramate is my anticonvulsant of choice. 200/mg per day. I don’t have any of the side effects people usually complain about.

How did that CGRP therapy turn out for you? It’s been a year since your post.