Colleen, after RCHOP. (1st chemo) and radiation my bone marrow is "tired" had Reclast in the past as I completed second ( first gyn) chemo also completed 9 rounds of Doxil(3rd chemo) June 2021. This last round of chemo had me chasing relief from ever-changing GI, mod-high fatigue, anorexia, depression ie. decreased Quality of life. Now, after 6 m break I feel mentally able to try Taxol, 3weeks on one off but: 1. my blood level are still low. 2. I'm having lt-mod fatigue. 3. Some discomfort from tumor load multiple/mod. growth MNA liver/lungs. My concern is whether chemo is additive to my quality or diminishing. My wishes are to protect my family from the extended ugly side of prolonged, invasive/ infection/ traumatic treatment ...when is it too far reaching for our own good? I know we don't have all the answers but there is probability and I need some guidance. Thank you, Jen