I know this may sound dumb as it didn't help me who also gets migraines...however I do want to say my hub was getting 2 times per week minimum. He was taking 50 mlgrms of name brand Imitrex. The neuro Dr. said he wasn't getting enough oxygen breathing at night. And tested him, landed up getting a cpap machine. I was ticked off thought Dr was wrong...guess what? He was right. Once in a blue moon he gets them now. So if you get sleep apnea investigate the possibility. Worth a try.