@mild835, Sorry to hear that prednisone is causing sleep problems for you. I never had that side effect. According the this article, taking prednisone late evening would make it worse.

"Timing of Doses -- Prednisone mimics a hormone called cortisol. This is a hormone that the body releases at times of stress.1
Cortisone levels are highest in the morning and gradually taper down as the day goes on. To reduce some side effects, like insomnia, once-daily doses should be taken in the morning with breakfast. Taking the dose of prednisone too late in the evening may affect your sleep." -- How to Lessen Your Prednisone Side Effects - Verywell Health: https://www.verywellhealth.com/lessening-prednisone-side-effects-1941741

The article goes on to say "Getting plenty of rest is also essential. This can be difficult because prednisone can interfere with sleep. One way to cope is to improve your sleep hygiene. This includes avoiding food and electronics before bedtime and sleeping in a cool, dark room. Some people also benefit from melatonin supplements available over the counter at drugstores."

The Sleep Foundation has some information on teas that may help you sleep better --- Drinking the Right Tea Can Help You Sleep: https://www.sleepfoundation.org/best-tea-for-sleep

Have you discussed your problem with insomnia with your doctor to see if they might have some suggestions?

I split my dose. One in the morning one in the evening about 12 hours apart. Ask your doctor.

I know many here will disagree but because the pain at night into morning was so unbearable I decided to take my prednisone’s at dinner time thinking it would help more then. I also read once that there is a time released medication (I need to find the name of it again) that kicks in around 2am when inflammation is the worst. Anyway I have no problem falling sleep. I might have a little more energy around 9pm to do some stretching and other exercises. I read or watch tv and then find myself falling sleep against my will on the couch around midnight so I go to bed and fall asleep immediately. I think the time between dinner and a late bedtime appears to be ample for me. I get up around 7-8 am each morning so I get between 6-8 hours sleep depending on when I go to bed.

I think the half life of prednisone is 24 to 36 hours. Not sure it would make any difference. But you have nothing to loose