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Melatonin and PMR

Polymyalgia Rheumatica (PMR) | Last Active: Apr 11, 2022 | Replies (45)

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@abbeyc

I will have to look for it. I don't disagree that you know what you are talking about. I am by no means a medical expert. But I do notice that my achiness and stiffness get worse as soon as night time falls so I think our bodies become aware and something happens with the inflammation. I read this is one reason it becomes so painful for us overnight into the morning besides the fact that we are not moving.

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Replies to "I will have to look for it. I don't disagree that you know what you are..."

I’m not a medical expert either. I was just sharing an article from a reliable source that was from a different perspective. That’s why I was wanting to read the article you mentioned.

There is evidence that people with PMR should take their prescribed dose of prednisone later in the day, even just before bed. After my PMR Diagnosis I was taking 15MGM of prednisone in the morning as directed by my rheumatologist and it wasn’t working after three days. So I switched to taking it before bed and bingo the next morning I felt great relief. I now take it after dinner so I am taking it with food to reduce digestive problems and it works well for me. The study I said inflammation occurs at night and you need the prednisone most at 3AM so you quell the inflammation and wake up feeling less stiff and sore. Just food for thought. Best wishes to all for good results.