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Replies to "Welcome @abbeyc, What you mentioned about Melatonin and inflammation is interesting. I haven't seen that and..."
Polymyalgia Rheumatica (PMR) | Last Active: Apr 11, 2022 | Replies (45)
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Welcome @abbeyc, What you mentioned about Melatonin and inflammation is interesting. I haven't seen that and would love to read it if you can remember where you saw the article. From what I've read, Melatonin possesses anti-inflammatory properties.
"Melatonin has been shown to possess anti-inflammatory effects, among a number of actions. Melatonin reduces tissue destruction during inflammatory reactions by a number of means. Thus melatonin, by virtue of its ability to directly scavenge toxic free radicals, reduces macromolecular damage in all organs."
-- Melatonin and its relation to the immune system and inflammation: https://pubmed.ncbi.nlm.nih.gov/11268363/
Are you currently taking prednisone for your PMR?
Replies to "Welcome @abbeyc, What you mentioned about Melatonin and inflammation is interesting. I haven't seen that and..."
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I will have to look for it. I don't disagree that you know what you are talking about. I am by no means a medical expert. But I do notice that my achiness and stiffness get worse as soon as night time falls so I think our bodies become aware and something happens with the inflammation. I read this is one reason it becomes so painful for us overnight into the morning besides the fact that we are not moving.