Hi @oldhen PMR and its companion disorder Giant Cell Arteritis are autoimmune disorders with genetic markers that affect people, usually over 50, most often of European ancestry, and women more often than men. The average annual rate of PMR in the US is 52.5 per 100,000 patients. (Cecil and Goldman's Textbook of Medicine).For me, PMR was pain and stiffness on a scale of 10 in my whole body - from the neck to the feet. Sometimes in the mornings I felt I would faint from the pain. It eased up a little in the night, but always returned. I had it for a year prior to diagnosis and also developed Giant Cell Arteritis. (About 30% of those with PMR develop Giant Cell Arteritis). The earliest record of GCA dates back to the 10th century so these diseases are not new. Through all this I had osteoarthritis of my shoulder that is slowly getting better after 9 months of Physical Therapy. I had COVID vaccines, booster and flu shot with no adverse symptoms. My PMR was triggered by an ankle injury. My aunt's was triggered by a back injury. I hope you are able to find relief.