Hi @ritchie, I agree with Ginger about meds affecting people differently and at different times. I'm so sorry to hear you are suffering, hopefully the pain will subside and dissipate quickly 🙁 I also have been taking Gabapentin for a year now, and I'll probably be taking it the rest of my life in order to function, which is ok by me. I'm not a doctor, mind you, but I do know that 100mg is a very low dose and in my experience I needed to increase that dose to feel its effects. It did take some time to feel it, but once I found my sweet spot, I have been able to fluctuate my doses as need be. My doctor said usually 300mg is where people will start to feel it working. I take 600-900mg at a time, 4x/day, but that's me - and my afflictions are very different, possibly. I would suggest staying in open communication with your doctor about it, because Gaba is a very easy and safe medicine to utilize and it has a large amount of wiggle room as far as dosage goes, and he/she'll be wanting to know what's working and vice versa. I wish you all the best of luck and many pain-free days ahead!